Do you know what is MTFHR? It’s not a cuss word

MTHFR (methylenetetrahydrofolate reductase) is an enzyme that plays a crucial role in the methylation process, which is involved in numerous biochemical reactions in the body. The MTHFR gene provides instructions for making the MTHFR enzyme, and certain genetic variations in this gene can affect its function. About 30-40% of the population have this genetic mutation that affect heir ability to utilize B vitamins. These patients have trouble detoxing, tend to have mood disorders, addiction personality, ADHD, history of miscarriages or birth defects, autism, chemical sensitivities, etc.

In the context of MTHFR, functional medicine practitioners recognize the impact of genetic variations and their influence on methylation and overall health.

Here are some key points regarding MTHFR and the functional medicine approach:

1. MTHFR Genetic Variations: Certain variations in the MTHFR gene, particularly the C677T and A1298C mutations, can lead to reduced enzyme activity. This can impact methylation processes and potentially affect various bodily functions, including detoxification, neurotransmitter production, hormone regulation, and DNA repair.

2. Methylation and Health Implications: Impaired methylation due to MTHFR gene variations has been associated with various other health conditions, such as cardiovascular disease, neural tube defects, mental health disorders, fertility issues, and chronic inflammation. However, it's important to note that MTHFR variations alone do not necessarily cause these conditions and that other genetic and environmental factors contribute as well.

Genes do not determine what happens but they pave the path. Epigenetics determines the outcome instead.

Genes play a fundamental role in shaping our physical and biological characteristics, but they alone do not determine our ultimate outcomes. Instead, genes act as a blueprint, paving the path for our development and potential. Epigenetics, a fascinating field of study, sheds light on the complex interplay between genes and the environment. Epigenetic modifications refer to chemical changes that occur on our DNA, effectively influencing gene expression and activity. These modifications can be influenced by a range of external factors, such as nutrition, stress, and lifestyle choices. Through epigenetic changes, our genes can be turned on or off, affecting how they function and interact with the environment. This intricate dance between genes and epigenetics demonstrates that while genes provide the foundation, our experiences and environment play a crucial role in shaping who we are and our ultimate outcomes. Epigenetics highlights the potential for change and adaptation, offering a promising avenue for understanding the complex interplay between nature and nurture.

3. Functional Medicine Approach: Functional medicine practitioners take an individualized approach to MTHFR-related concerns. They assess a patient's genetic profile, medical history, lifestyle factors, and laboratory tests to gain a comprehensive understanding of their unique needs. This enables them to develop personalized treatment plans aimed at optimizing methylation processes and overall health.

4. Nutritional Support: Functional medicine practitioners often emphasize a nutrient-dense diet that supports methylation and addresses potential nutrient deficiencies associated with MTHFR variations. This may include increasing intake of folate-rich foods, as well as supporting nutrients like vitamins B12, B6, and riboflavin. Individuals should avoid Folic acid, which is B9 in a synthetic form added to food, otc vitamins etc. They should use Methylfolate or folinic acid instead. Your functional medicine provider will likely recommend methylated forms of vitamins and minerals for better absorption and utilization  (such as active B vitamins) .

5. Lifestyle Modifications: Functional medicine takes a holistic approach by considering lifestyle factors that can impact methylation and overall well-being. Recommendations may include stress reduction techniques, regular physical activity, toxin avoidance, and optimizing sleep quality.

6. Personalized Supplementation: Depending on individual needs and test results, functional medicine practitioners may recommend targeted supplementation to support methylation pathways. This could involve specific forms of folate, vitamin B12, or other nutrients that support methylation and address specific deficiencies.

It's important to consult with a qualified healthcare professional, such as a functional medicine practitioner, who can provide personalized guidance based on your specific genetic profile, health history, and individual needs. Angelica Clark PA-C, IFMCP is a certified functional medicine practitioner who can help you supplement correctly to improve methylation and correct your deficiencies caused by this genetic mutation or defect.

www.clarkwellnesswaco.com

254-386-8149

References:

- The Institute for Functional Medicine. (n.d.). About Functional Medicine. Retrieved from https://www.ifm.org/functional-medicine/about-functional-medicine/

- National Human Genome Research Institute. (2021). MTHFR gene. Retrieved from https://www.genome.gov/genetics-glossary/methylenetetrahydrofolate-reductase

- Bailey, L. B., & Gregory, J. F. (1999). Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: Metabolic significance, risks and impact on folate requirement. The Journal of Nutrition, 129(5), 919-922.

3 Simple and Natural Ways to Treat Migraine Headaches

Migraine headaches can be debilitating, affecting individuals physically and mentally. While there are various treatment options available, many people seek natural remedies to alleviate their migraine symptoms. In this article, we will explore three easy and simple ways to treat migraine headaches naturally, offering potential relief without relying on medication.

1. Identify Triggers and Make Lifestyle Adjustments:

Identifying triggers is crucial in managing migraines. Triggers can vary from person to person but commonly include stress, certain foods (such as chocolate, caffeine, or aged cheese), hormonal changes, and environmental factors.

Keep a calendar and log your episodes and description of your symptoms.

Once you identify your triggers, make the following lifestyle adjustments:

- Maintain a Consistent Sleep Schedule: Establish regular sleep patterns and ensure you get enough sleep each night. Lack of sleep or irregular sleep patterns can trigger migraines.

- Manage Stress: Practice stress-reducing techniques such as deep breathing exercises, meditation, yoga, or engaging in hobbies and activities you enjoy. Regular exercise can also help reduce stress levels.

- Stay Hydrated: Dehydration can trigger migraines in some individuals. Drink plenty of water throughout the day and limit your consumption of sugary or caffeinated beverages. Many people don't realize but pain and discomfort perception are augmented when dehydrated.

- Avoid Trigger: Identify and avoid foods that commonly trigger migraines for you. Keep a food diary to track your diet and potential triggers. Alcohol, sulfite in wine and sugar are triggers for many.

- Create a Calm Environment: Minimize exposure to bright lights, loud noises, and strong odors that may trigger migraines. Consider using relaxation techniques or finding a quiet, dimly lit space during a migraine attack.

2. Use Essential Oils for Relief:

Essential oils have been used for centuries to alleviate various ailments, including migraines. Certain oils have shown promising results in reducing headache symptoms. Consider the following essential oils:

- Peppermint Oil: Apply diluted peppermint oil to the temples, forehead, and back of the neck for a cooling effect that may help ease migraine pain.

- Lavender Oil: Inhaling lavender oil or applying it topically to the temples and wrists may promote relaxation and reduce migraine symptoms.

- Eucalyptus Oil: This oil can help relieve sinus congestion and headaches associated with it. Diffuse eucalyptus oil or inhale it for respiratory relief during migraines.

Note: Always dilute essential oils properly and conduct a patch test before applying them topically.

3. Practice Relaxation Techniques and Stress Management:

Stress is a common trigger for migraines. Learning to manage stress effectively can help reduce the frequency and severity of migraine attacks. Consider incorporating the following relaxation techniques into your routine:

- Deep Breathing Exercises: Practice deep, slow breathing to promote relaxation and reduce stress.

- Progressive Muscle Relaxation: Tense and relax each muscle group in your body to release tension and induce relaxation.

- Stretching and Meditation: Engage in gentle stretching. Prayer and meditating on the bible can help you calm the mind, reduce stress, and promote overall well-being.

- Biofeedback: This technique helps you become aware of your body's response to stress and teaches you how to control physical responses to prevent migraines.

While migraines can be challenging to manage, there are simple and natural ways to find relief. By identifying triggers, making lifestyle adjustments, using essential oils, and practicing relaxation techniques, individuals may experience a reduction in the frequency and intensity of their migraines. Remember, every person's experience is unique, so finding the right combination of natural remedies may require some trial and error. If migraines persist or worsen, it's essential to consult with a healthcare professional for further evaluation and guidance. If you have had a work up by neurologist or PCP and you are still struggling and the work up was normal, Angelica Clark PA-C, IFMCP is a certified Functional Medicine Practicioner in Waco Texas, she can help you find out the root cause of your Headaches.

www.clarkwellnesswaco.com

254-386-7149

Note: This article is for informational purposes only and should not replace professional medical advice.

Myofunctional therapy

Myofunctional therapy is a specialized form of therapy that focuses on the muscles of the face, mouth, and throat. It involves exercises and techniques designed to improve the function and coordination of these muscles, which can have various benefits for sleep and metabolism.

Here's how myofunctional therapy may help improve sleep and metabolism:

1. Sleep Apnea and Snoring: Myofunctional therapy can be beneficial for individuals with sleep apnea or snoring issues. By targeting the muscles involved in breathing and maintaining an open airway, such as the tongue and throat muscles, myofunctional exercises aim to strengthen and improve their function. This can help reduce airway obstructions during sleep, leading to decreased snoring and improved breathing patterns.

2. Tongue Posture and Swallowing: Proper tongue posture and swallowing patterns play a crucial role in overall oral and facial muscle function. Myofunctional therapy addresses any dysfunctional patterns and helps individuals develop correct tongue posture and swallowing techniques. This can improve the muscle tone and coordination in the oropharyngeal area, which may positively impact sleep quality and breathing.

3. Metabolism and Weight Management: Myofunctional therapy can indirectly contribute to improved metabolism and weight management. By improving breathing patterns, it may enhance oxygenation and energy utilization within the body. Additionally, as proper tongue posture and swallowing patterns improve, it can positively affect digestion and nutrient absorption, which are essential for a healthy metabolism.

It's important to note that myofunctional therapy should be administered by a trained therapist who can assess individual needs and provide personalized guidance. The therapy is often performed alongside other interventions recommended by healthcare professionals, such as dental or sleep specialists, to address specific sleep-related concerns.

While there is a growing body of anecdotal evidence supporting the use of myofunctional therapy for sleep and metabolism, further research is needed to establish its efficacy and understand the underlying mechanisms.

Please consult with a qualified airway specialist or myofunctional therapist for personalized advice and guidance regarding myofunctional therapy and its potential benefits for sleep and metabolism.

References:

1. Guimarães, K. C. et al. (2009). Tongue Fat and Its Relationship to Obstructive Sleep Apnea. Sleep, 32(12), 1547-1554.

2. Guimarães, K. C. et al. (2010). Effects of Orofacial Myofunctional Therapy on Sleep Apnea: A Systematic Review. Sleep and Breathing, 14(2), 109-118.

3. Patel, P. et al. (2020). Impact of Myofunctional Therapy on Upper Airway Morphology in Adults: A Systematic Review. Journal of Oral Rehabilitation, 47(6), 795-807.

4. Rosa, G. M. et al. (2021). Myofunctional Therapy for Snoring and Obstructive Sleep Apnea: A Systematic Review and Meta-analysis. Sleep Medicine Reviews, 59, 101446.