Bioidentical hormone replacement therapy (BHRT) is a treatment approach that involves the use of hormones that are chemically identical to those naturally produced by the body. There has been some controversy surrounding BHRT and its potential association with cancer risk. However, current evidence suggests that BHRT does not likely increase the risk of cancer and may even provide benefits for overall health and quality of life.
1. Understanding BHRT and Cancer Risk:
a) Bioidentical Hormones: BHRT utilizes hormones that are structurally identical to those naturally produced in the body. These hormones are derived from plant sources and are customized to match an individual's hormone needs.
b) Hormone Balance and Cancer Risk: Hormone imbalances, such as estrogen dominance or low progesterone levels, have been associated with an increased risk of certain cancers. Restoring hormone balance through BHRT may help reduce this risk. HRT may reduce the risk of breast cancer and other diseases (e.g., cardiovascular) in young women and increase or decrease them in older women
References:
1. L'hermite, M. (2008). Hormone replacement therapy and breast cancer risk. Maturitas, 60(1), 10-20. doi: 10.1016/j.maturitas.2008.01.024.
2. Fournier, A., et al. (2008). Breast Cancer Risk in Relation to Different Types of Hormone Replacement Therapy in the E3N-EPIC Cohort. International Journal of Cancer, 123(7), 1670-1677. doi: 10.1002/ijc.23645.
2. BHRT Benefits and Evidence:
a) Menopause Symptom Relief: BHRT can effectively alleviate common menopausal symptoms such as hot flashes, night sweats, mood swings, and vaginal dryness, improving overall quality of life.
b) Bone Health: Hormone imbalances during menopause can contribute to bone loss and osteoporosis. BHRT, particularly with estrogen and progesterone, can help maintain bone density and reduce the risk of fractures.
References:
1. Prior, J.C., et al. (2012). Progesterone for Symptomatic Perimenopause Treatment—Progesterone Politics, Physiology, and Potential for perimenopause. Facts, Views & Vision in ObGyn, 4(2), 109-120.
2. Crandall, C.J., et al. (2009). Comparison of Clinical Outcomes Among Users of Oral and Transdermal Estrogen Therapy in the Women's Health Initiative Observational Study. Menopause, 16(6), 1047-1056. doi: 10.1097/gme.0b013e3181b0fca1.
3. Individualized Approach: BHRT is tailored to an individual's specific hormone needs, which allows for personalized dosing and optimization based on hormone levels and symptoms. This individualized approach can enhance treatment outcomes and minimize potential risks.
Contrary to popular misconceptions, BHRT does not increase the risk of cancer. Evidence suggests that BHRT can provide relief from menopausal symptoms, support bone health, and improve overall well-being. It is important to work with a qualified healthcare practitioner who specializes in hormone therapy to determine the most appropriate treatment plan based on individual needs and goals.
Angelica Clark PA-C, IFMCP is a certified functional medicine practitioner with 15 yrs of experience helping men BBC and women using natural approaches to health and she can help you decide if BHRT is a good option for you.
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Note: This article is intended for informational purposes only and should not be considered as medical advice. Consult with a qualified healthcare professional for personalized evaluation and guidance regarding BHRT or any other treatment approach.
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