Uterine Fibroids: The Hidden Connection Between Toxins and Your Hormones
- Angelica Clark
- Nov 16
- 5 min read
What You're Actually Breathing In (And Why It Matters)
You make healthy choices. You eat organic when possible. You exercise. You manage stress. So why do you have uterine fibroids?
The answer might be hiding in places you never look: your plastic water bottle, that receipt from the store, the shampoo in your shower.
Everyday toxins are silently disrupting your hormones, and fibroids might be the result.
The Estrogen-Fibroid Connection
Here's the biological reality: uterine fibroids are estrogen-dependent. They grow when estrogen levels are high, shrink when they drop (like during menopause), and respond to your hormonal environment.
But here's what most women don't realize: it's not just about how much estrogen your body makes. It's about how much toxic chemicals are pretending to be estrogen.
These chemicals, called endocrine disruptors, trick your body. They act like estrogen even though they're not. Your cells treat them like real hormones, and your fibroids grow as a result.
The Usual Suspects: Hidden Toxins Affecting Fibroids
Bisphenol-A (BPA)
You've probably heard of BPA. It's in plastic bottles, canned food linings, and thermal paper receipts. But here's what most people don't know: women with fibroids have measurably higher BPA levels than women without them.
Research shows BPA actually stimulates fibroid cells to grow. It increases the expression of growth factors that feed fibroid development.
Where it hides:
Plastic beverage bottles (especially when heated)
Canned soups, beans, and tomatoes
Dental sealants
Register receipts
Some plastics marked #7
Phthalates
These are everywhere. Phthalates are in anything fragranced—perfumes, deodorants, hair products, even "fragrance-free" items because companies use them to mask other smells.
They're also in:
Vinyl flooring and shower curtains
Plastic food storage containers
Processed meats and cheeses
Some nail polishes and cosmetics
The frustrating part? They're often hidden under the generic label "fragrance," so you can't easily identify them. Studies show women with elevated phthalate levels have significantly higher fibroid rates.
Persistent Organic Pollutants (POPs)
This is the scariest category because they're nearly impossible to avoid completely. POPs include:
Old pesticides still in the environment:
DDT (banned in the 1970s but still in soil and water)
PCBs (industrial chemicals banned decades ago but still contaminating rivers and lakes)
Where they persist:
Fatty fish and seafood
Dairy products
Non-organic vegetables and grains
Drinking water in some regions
Even though these were banned, they don't break down. They accumulate in your body fat and continue disrupting your hormones decades later.
Cadmium
This heavy metal is a direct fibroid promoter. It acts like synthetic estrogen in your reproductive organs. Women get exposed through:
Non-organic leafy greens and root vegetables
Shellfish and certain fish
Rice
Cigarette smoke
Low levels of cadmium have been shown to directly stimulate fibroid cell growth.
The Personalized Approach: Genetic Testing for Estrogen Metabolism
Here's where conventional medicine often misses the mark. Everyone's body metabolizes estrogen differently. And this difference is determined by your genes.
Why Genetic Testing Matters
If your genes code for slower estrogen metabolism, you're holding onto excess estrogen longer. This is like leaving the hormone accelerator pressed down continuously. Your fibroids have more "fuel" to grow.
Understanding your genetic profile changes everything about treatment:
Slow metabolizers need:
Different dietary support
Targeted supplementation to speed detoxification
Specific foods that enhance their unique metabolic pathway
More aggressive toxin avoidance
Fast metabolizers have different needs:
Different nutritional approaches
Often better fibroid prognosis with standard interventions
How to Get Tested
Genetic testing for estrogen metabolism typically includes:
Phase 1 detoxification genes (CYP1A2, CYP1B1)
Phase 2 detoxification genes (COMT, MTHFR)
Estrogen metabolism pathways
A functional medicine doctor or naturopath can order these tests. They show your individual metabolism pattern—not just a generic prescription.
With this information, treatment becomes personalized rather than one-size-fits-all.
Two Powerful Supplements Most Doctors Don't Mention
Nattokinase: The Fibrin-Dissolving Enzyme
Uterine fibroids are made of tissue held together by fibrin—essentially internal scar tissue. Nattokinase is an enzyme extracted from fermented soy that breaks down excess fibrin.
How it works:
Dissolves fibrin deposits naturally
Reduces inflammation in fibroid tissue
Improves blood flow to affected areas
Supports the body's natural fibrolysis (tissue breakdown)
What research shows:
Effective at reducing fibroid size in some women
Works synergistically with other treatments
Generally safe with minimal side effects
Takes 3-6 months to see results
How to use it:
Typical dose: 2,000-3,000 Fibrinolytic Units (FU) daily
Take on an empty stomach (morning before breakfast)
Consistency is key—this isn't a quick fix
Serrapeptase: The Complementary Enzyme
Serrapeptase works alongside nattokinase. This protease enzyme breaks down dead tissue and biofilm—the protective covering fibroids use to hide from your immune system.
Why it matters:
Helps your immune system recognize fibroid tissue
Reduces inflammation and swelling
Works on scar tissue
Supports natural healing responses
Common protocol:
Often used alongside nattokinase
Dose: 40,000-60,000 units daily
Also takes on empty stomach
3-6 month treatment window
The combination approach: Women using both nattokinase and serrapeptase together report better results than either alone. The two enzymes work on different aspects of fibroid tissue:
Nattokinase dissolves the fibrin matrix
Serrapeptase breaks down protective biofilm and dead tissue
This allows the body's natural healing systems to address the fibroid more effectively.
Your Action Plan: Taking Control
Immediate Steps (This Week)
Reduce toxin exposure:
Stop using plastic bottles; switch to glass
Buy organic leafy greens and root vegetables
Choose fragrance-free products (or those scented with essential oils only)
Decline receipts or use digital options
Order genetic testing:
Talk to your functional medicine provider
Get tested for estrogen metabolism pathways
Understand your personal detox capacity
Start targeted supplementation:
Begin nattokinase (empty stomach, morning)
Add serrapeptase if recommended
Give it time—3-6 months minimum
Ongoing Changes (This Month)
Increase fiber intake (supports estrogen elimination)
Add cruciferous vegetables (broccoli, Brussels sprouts, cauliflower)
Use glass and stainless steel for food storage
Filter your drinking water
Switch personal care products to clean brands
Monitoring Progress (Ongoing)
Track symptom changes (heavy bleeding, pain, pressure)
Get ultrasounds at 3-month intervals
Work with practitioner to adjust protocol
Notice energy and hormonal symptom improvements
Why This Approach Works Differently
Most conventional medicine treats fibroids as a problem to surgically remove. Functional medicine asks: Why did they develop in the first place?
By addressing:
Toxin exposure and detoxification
Genetic metabolism patterns
Inflammation at the tissue level (with nattokinase and serrapeptase)
Hormonal environment
...you're actually changing the conditions that allow fibroids to thrive.
The Bottom Line
Your fibroids aren't a random malfunction. They're your body's response to a hormonal environment disrupted by environmental chemicals and your unique genetic detoxification capacity.
Understanding your genetic metabolic pattern gives you power. Adding enzyme support removes the tissue inflammation. Reducing toxin exposure stops feeding the problem.
This isn't fast. It isn't glamorous. But it works with your body's actual mechanisms rather than against them.
And for many women, it's the difference between hysterectomy and finally feeling normal again.
Ready to understand your personal estrogen metabolism? Get genetic testing. Ready to support tissue healing? Start nattokinase and serrapeptase. Ready to detoxify your environment? Begin eliminating hidden toxin sources.
Small changes. Big impact. Your fibroids don't stand a chance. Be sure to consult with your doctor before trying these recommendations. This is for educational purposes only.









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